abstract：OBJECTIVE:To determine the clinical epidemiology of invasive group A streptococcal disease (IGASD) and identify predictors of admissions into an intensive care unit (ICU). DESIGN:A cross-sectional study. SETTING:Retrospective review of data. PATIENTS:A total of 204 patients hospitalized throughout the state of Flori...

journal_title：Intensive care medicine

authors： Mulla ZD

更新日期：2002-12-01 00:00:00

abstract：:The metabolic changes associated with critical illness involve several pathways acting at different steps of the utilization of nutritive substrates. The understanding of the role of these pathways and of their complex regulation has led to the development of new strategies for the metabolic and nutritional management...

journal_title：Intensive care medicine

authors： Biolo G,Grimble G,Preiser JC,Leverve X,Jolliet P,Planas M,Roth E,Wernerman J,Pichard C,European Society of Intensive Care Medicine Working Group on Nutrition and Metabolism.

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:To compare outcome prediction using the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA), two of the systems most commonly used to evaluate organ dysfunction in the intensive care unit (ICU). DESIGN:Prospective, observational study. SETTING:Thirty-one-bed, universit...

journal_title：Intensive care medicine

authors： Peres Bota D,Melot C,Lopes Ferreira F,Nguyen Ba V,Vincent JL

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVE:We report the first patient to developed abdominal compartment syndrome (ACS) with intrahepatic portal venous gas (IHPVG) and pneumatosis cystoides intestinalis following emergency upper gastrointestinal endoscopy. CASE PRESENTATION:A 53-year-old man underwent an emergency upper gastrointestinal endoscopy fo...

journal_title：Intensive care medicine

authors： Hayakawa M,Gando S,Kameue T,Morimoto Y,Kemmotsu O

更新日期：2002-11-01 00:00:00

abstract：:Recombinant activated factor VII (rFVIIa, 'NovoSeven') is indicated for the treatment of spontaneous and surgical bleeding in patients with haemophilia A or B with antibodies to factors VIII or IX (FVIII or FIX) worldwide, and in patients with acquired haemophilia in Europe. In vitro cell models have demonstrated that...

journal_title：Intensive care medicine

authors： Von Depka M

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:Antithrombin exerts direct effects on neutrophils by inhibiting chemokine-induced migration. This study examined the potency of different pharmaceutical antithrombin preparations in inhibiting neutrophil chemotaxis toward interleukin 8. METHODS:Cell migration was tested by the leading front assay in modified...

journal_title：Intensive care medicine

authors： Kaneider NC,Rabensteiner A,Reinisch CM,Dunzendorfer S,Wiedermann CJ

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To compare noninvasive positive pressure ventilation (NPPV) vs. invasive mechanical ventilation in AIDS patients with Pneumocystis carinii pneumonia (PCP)-related acute respiratory failure (ARF). DESIGN:A single-center, prospective, case-control trial. SETTING:An ICU of a private tertiary hospital specializ...

journal_title：Intensive care medicine

authors： Confalonieri M,Calderini E,Terraciano S,Chidini G,Celeste E,Puccio G,Gregoretti C,Meduri GU

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To assess the outcome of intensive care unit (ICU) treatment in patients with hematological malignancies. DESIGN AND SETTING:Retrospective cohort study in the medical ICU of a university hospital. PATIENTS:104 critically ill patients after receiving conventional chemotherapy or autologous hematopoietic stem...

journal_title：Intensive care medicine

authors： Kroschinsky F,Weise M,Illmer T,Haenel M,Bornhaeuser M,Hoeffken G,Ehninger G,Schuler U

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To report the occurrence of life-threatening hyperkalaemia following treatment with therapeutic thiopentone coma. SETTING:The neurosurgical intensive care units of Royal North Shore Hospital and Liverpool Hospital, Sydney, Australia. PATIENTS:Three patients treated with theraputic thiopentone coma. One pati...

journal_title：Intensive care medicine

authors： Cairns CJ,Thomas B,Fletcher S,Parr MJ,Finfer SR

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:We undertook this study to evaluate the influence of the inspiration:expiration (I:E) ratio on intracranial pressure and cerebral perfusion in patients with acute stroke. DESIGN:Ventilated patients with acute stroke were examined under a protocol involving variations of I:E ratio from 1:2 to 1:1 to 1:2 under...

journal_title：Intensive care medicine

authors： Georgiadis D,Schwarz S,Kollmar R,Baumgartner RW,Schwab S

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To test the hypothesis that, during high-frequency oscillatory ventilation (HFOV) of pigs with acute lung injury, the oxygenation index (OI = Paw*FIO(2)*100/PaO(2)) is minimal at the lowest continuous distending pressure (Paw), where the physiological shunt fraction is below 0.1 (Paw(optimal)). DESIGN AND SE...

journal_title：Intensive care medicine

authors： van Genderingen HR,van Vught JA,Jansen JR,Duval EL,Markhorst DG,Versprille A

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:The pressure-volume (P/V) curve has been proposed as a tool to adjust the ventilatory settings in cases of acute respiratory distress syndrome (ARDS). The aim of this study was to test the influence of P/V tracing methodology on the presence and value of the upper inflection point (UIP). METHODS:In 13 medica...

journal_title：Intensive care medicine

authors： Servillo G,De Robertis E,Maggiore S,Lemaire F,Brochard L,Tufano R

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVES:Controversy over the optimal intravenous fluid for volume resuscitation continues unabated. Our objectives were to characterize the demographics of physicians who prescribe intravenous colloids and determine factors that enter into their decision to choose a colloid. DESIGN:Questionnaire with 61 items. PAR...

journal_title：Intensive care medicine

authors： Miletin MS,Stewart TE,Norton PG

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Dislocation of the heart is a rare complication of thoracic blunt trauma. A high index of suspicion of pericardium rupture is necessary to formulate an early diagnosis to reduce morbidity and mortality. PATIENTS:A 23-year-old man suffered a blunt thoracoabdominal trauma and was admitted 3 days later to a un...

journal_title：Intensive care medicine

authors： Piazza O,De Robertis E,Fraioli G,Tufano R

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To identify objective trends of the course of illness that might be used as benchmarks in the auditing of the organization/performance of Intensive Care Units (ICU). DESIGN:Retrospective analysis. PATIENTS AND SETTING:A group of 12,615 patients and 55,464 patient-days prospectively collected in 89 ICUs of 1...

journal_title：Intensive care medicine

authors： Iapichino G,Radrizzani D,Ferla L,Pezzi A,Porta F,Zanforlin G,Miranda DR

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To define the different types of costs incurred in the care of critically ill patients and to describe some of the most commonly used methods for measuring and allocating these costs. DESIGN:Literature review. Definitions for opportunity, direct and indirect, fixed, variable, marginal, and total costs are de...

journal_title：Intensive care medicine

authors： Jegers M,Edbrooke DL,Hibbert CL,Chalfin DB,Burchardi H

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:The association of acute-phase reaction and outcome of patients with acute vascular diseases is controversial. The prognostic value of admission C-reactive protein (CRP) in patients with acute aortic aneurysm or dissection has not yet been investigated. DESIGN AND SETTING:Cohort study including 255 consecuti...

journal_title：Intensive care medicine

authors： Schillinger M,Domanovits H,Bayegan K,Hölzenbein T,Grabenwöger M,Thoenissen J,Röggla M,Müllner M

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVES:To document the effect of neurocritical care, delivered by specialist staff and based on protocol-driven therapy aimed at intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targets, on outcome in acute head injury. DESIGN:Retrospective record review to compare presentation, therapy and outcom...

journal_title：Intensive care medicine

authors： Patel HC,Menon DK,Tebbs S,Hawker R,Hutchinson PJ,Kirkpatrick PJ

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of some acid-base abnormalities on blood capacity of transporting CO(2). DESIGN:Prospective study. SETTING:General and Cardiosurgical ICUs of a University hospital. PATIENTS:Six groups of ten patients characterized by: metabolic alkalosis; respiratory alkalosis; absence of acid-b...

journal_title：Intensive care medicine

authors： Cavaliere F,Antonelli M,Arcangeli A,Conti G,Pennisi MA,Proietti R

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:To establish a preliminary list of critical incidents (CIs) associated with mechanical ventilation and to describe a CI reporting method. DESIGN:A list of CIs was established based on a consensus among ICU caregivers. The list was compared to CIs collected prospectively during a predefined study period. SE...

journal_title：Intensive care medicine

authors： Auriant I,Reignier J,Pibarot ML,Bachat S,Tenaillon A,Raphael JC

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:To examine the phenomenon of inappropriate triggering caused by an in-line suction catheter. DESIGN:We used a test lung to assess inappropriate triggering in four ventilators with both pressure and flow triggering. RESULTS:With pressure triggering, inappropriate triggering occurred only in the presence of P...

journal_title：Intensive care medicine

authors： Al-Khafaji A,Manning HL

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:Trunk position at 45 degrees from the horizontal is associated with a decreased risk of gastroesophageal aspiration. The objectives of this study were to determine the accuracy of trunk flexion estimates compared to a reference standard measurement, and to determine agreement about trunk flexion among ICU cl...

journal_title：Intensive care medicine

authors： McMullin JP,Cook DJ,Meade MO,Weaver BR,Letelier LM,Kahmamoui K,Higgins DA,Guyatt GH

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the perceived health and cognitive status in survivors of chronic obstructive pulmonary disease (COPD) exacerbations requiring mechanical ventilation. DESIGN AND SETTING:Prospective controlled cohort study in a respiratory intermediate intensive care unit. PATIENTS:Sixty-three COPD patients at t...

journal_title：Intensive care medicine

authors： Ambrosino N,Bruletti G,Scala V,Porta R,Vitacca M

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of prone positioning on systemic hemodynamics, intra-abdominal pressure (IAP), plasma disappearance rate of indocyanine green (PDR(ICG)), and gastric intramucosal to arterial PCO2 difference (Pi-aCO2). DESIGN AND SETTING:Prospective randomized study in the intensive care unit of a ...

journal_title：Intensive care medicine

authors： Hering R,Vorwerk R,Wrigge H,Zinserling J,Schröder S,von Spiegel T,Hoeft A,Putensen C

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:a) to describe a non-barotraumatic ventilatory setting for independent lung ventilation (ILV); b) to determine the utility of single lung end-tidal CO(2) (EtCO(2)) monitoring to evaluate the ventilation to perfusion (V/Q) matching in each lung during ILV and for ILV weaning. DESIGN:prospective study. SETTIN...

journal_title：Intensive care medicine

authors： Cinnella G,Dambrosio M,Brienza N,Giuliani R,Bruno F,Fiore T,Brienza A

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVES:(1) To demonstrate that metabolic parameters are better indicators of tissue hypoxia than regional and whole oxygen consumption (VO(2)). (2) To compare intramucosal pH (pHi) in different gastrointestinal segments. DESIGN:Prospective, interventional study. SETTING:Research laboratory at a university center....

journal_title：Intensive care medicine

authors： Dubin A,Estenssoro E,Murias G,Canales H,Sottile P,Badie J,Barán M,Pálizas F,Laporte M,Rivas Díaz M

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:The liver plays a key role in the inflammatory response during major surgery or infection. The influence of age on liver function and hepatic acute phase protein (APP) synthesis should be serially studied in elderly patients undergoing major abdominal surgery. DESIGN AND SETTING:Prospective and descriptive s...

journal_title：Intensive care medicine

authors： Suttner SW,Sürder C,Lang K,Piper SN,Kumle B,Boldt J

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Impairment of haemostasis has been described with slowly degradable medium molecular weight hydroxyethyl starch (MMW-HES), whereas rapidly degradable MMW-HES is generally considered to have no important effects on blood coagulation. This study was undertaken to investigate the effects of a rapidly degradable ...

journal_title：Intensive care medicine

authors： de Jonge E,Levi M,Büller HR,Berends F,Kesecioglu J

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVE:Evaluating the prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units (ICUs). DESIGN:Cross-sectional design. SETTING:ICUs of acute care hospitals that participated in the 1998 and 1999 national prevalence surveys. Data were collected on 1 day in each year. PATIENTS:Eight h...

journal_title：Intensive care medicine

authors： Bours GJ,De Laat E,Halfens RJ,Lubbers M

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of basic life support, time to first defibrillation and emergency medical service arrival time on neurologic outcome and expenses for hospital care in patients after cardiac arrest. SETTING:Large urban emergency medical services system and emergency department in a 2000-bed university...

journal_title：Intensive care medicine

authors： Bur A,Kittler H,Sterz F,Holzer M,Eisenburger P,Oschatz E,Kofler J,Laggner AN

更新日期：2001-09-01 00:00:00

abstract：:There has been little research on smoking cessation after critical illness. Smokers make up a high percentage of patients admitted to intensive care (ICU) and stopping smoking is one message that should be clearly given to recovering patients. The recovery period provides an important opportunity for patients to quit ...

journal_title：Intensive care medicine

authors： Jones C,Griffiths RD,Skirrow P,Humphris G

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVES:Previous studies on therapeutic interventions in sepsis have assumed stability of the measure of splanchnic blood flow throughout the study. We assessed the variability of splanchnic blood flow during stable global hemodynamics in eight patients with sepsis requiring treatment with dobutamine and/or norepine...

journal_title：Intensive care medicine

authors： Sakka SG,Reinhart K,Wegscheider K,Meier-Hellmann A

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To assess the effect of strict guidelines and a rigorous training program on variability in scoring the revised Acute Physiology and Chronic Health Evaluation (APACHE II). DESIGN AND SETTING:Prospective survey and intervention in the surgical ICU of a university teaching hospital. MEASUREMENTS:Seven experie...

journal_title：Intensive care medicine

authors： Polderman KH,Jorna EM,Girbes AR

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To report the feasibility of craniectomy with duraplasty in four patients with life-threatening encephalitis and, in particular, their long-term outcome. DESIGN:Report of four cases, analysis of the acute clinical course and neurological long-term sequelae. RESULTS:Generous craniectomy with duraplasty was p...

journal_title：Intensive care medicine

authors： Taferner E,Pfausler B,Kofler A,Spiss H,Engelhardt K,Kampfl A,Schmutzhard E

更新日期：2001-08-01 00:00:00

abstract：OBJECTIVE:To evaluate trends in mortality and related factors among trauma patients who developed acute respiratory distress syndrome (ARDS). STUDY:Observational study based on data prospectively gathered in computerized trauma registry. SETTING:Trauma intensive care unit (ICU) of 48 beds in level I trauma center. P...

journal_title：Intensive care medicine

authors： Navarrete-Navarro P,Rodriguez A,Reynolds N,West R,Habashi N,Rivera R,Chiu WC,Scalea T

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Short-latency somatosensory evoked potential (SSEP) monitoring has been reported to be useful in predicting neurological outcome in patients with cardiac arrest and hypoxic-ischemic encephalopathy. To obtain the immediate data of SSEP and evaluate the relationship between the presence of cortical activity and...

journal_title：Intensive care medicine

authors： Nakabayashi M,Kurokawa A,Yamamoto Y

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:To validate a simple method avoiding discard volumes in pediatric patients with indwelling arterial and venous lines. DESIGN:Zero-discarding was achieved by passive extracorporeal arteriovenous backflow via standard single pressure transducer equipment. We tested backflow distances (10, 20 and 30 cm beyond t...

journal_title：Intensive care medicine

authors： Weiss M,Fischer J,Boeckmann M,Rohrer B,Baenziger O

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:To measure water balance and changes in distribution, and the effect of giving supplementary albumin, early after a burn injury. DESIGN:Consecutive patients (matched groups) and healthy controls. SETTING:National burn unit in a Swedish university hospital. PATIENTS AND SUBJECTS:Eighteen patients with 18%-9...

journal_title：Intensive care medicine

authors： Zdolsek HJ,Lisander B,Jones AW,Sjöberg F

更新日期：2001-05-01 00:00:00

abstract：:During a 3-year period, a clinical diagnosis of invasive candidosis was made in 8 out of 2054 consecutive surgical intensive care unit (ICU) patients. These patients were retrospectively matched with 16 control patients who underwent similar surgical procedures and had a similar clinical course except for negative Can...

journal_title：Intensive care medicine

authors： Lepper PM,Wiedeck H,Geldner G,Essig A,Trautmann M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:A closed suction system (CS) maintains connection with the mechanical ventilator during tracheal suctioning and is claimed to limit loss in lung volume and oxygenation. We compared changes in lung volume, oxygenation, airway pressure and hemodynamics during endotracheal suctioning performed with CS and with a...

journal_title：Intensive care medicine

authors： Cereda M,Villa F,Colombo E,Greco G,Nacoti M,Pesenti A

更新日期：2001-04-01 00:00:00